The H2AFY Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to H2AFY, Histone Macro H2A1, MacroH2A, MACROH2A1.1, and mH2A1. This antibody recognizes Human, Mouse, and Rat antigen. The H2AFY Polyclonal Antibody has been validated for the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms